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Ooh! Aah! Ouch! Your pooch might be suffering from arthritis!

We all know that arthritis is a common ailment of old age but not many of us would know that it is the case with our pooches as well. If your pooch is not willing to play or work or has slowed down, he might be suffering from arthritis. But help is here at hand!

What is arthritis?

Arthritis comes from Greek word arthro-(joint) + -itis (inflammation). It refers to a group of conditions involving damage to the joints of the body. There are over 100 different forms of arthritis, the most common being osteoarthritis (degenerative joint disease), which is a result of trauma to the joint, infection of the joint, or age. Other arthritis forms are rheumatoid arthritis, psoriatic arthritis, and autoimmune diseases in which the body attacks itself. Septic arthritis is caused by joint infection while Gouty arthritis is caused by deposition of uric acid crystals in the joint, causing inflammation.

Canine arthritis: a common ailment

Arthritis not only affects humans but also it’s a common ailment in your loving pets; though dogs of all age group can suffer but it’s more frequently observed in older age. You can notice the change in your pet’s activity if you observe his behaviour. You can notice following changes in your dog’s behaviour:

  • Favouring a particular limb
  • Hesitancy to jump, run or climb stairs
  • Behavioural changes like sleeping more
  • Reduction in alertness
  • Seeming to have stiff & sore joints
  • Not willing to play
  • Joint enlargement or swelling
  • Weight gain

Probable causes of arthritis

Old age, joint infections, traumatic injury to joints, dietary imbalance, autoimmune diseases, hormonal imbalance, overweight & lack of exercise can act as predispository factor.

Diagnosing arthritis

If these symptoms persist for longer than 2-3 weeks, consult your veterinarian for correct diagnosis. Physical examination and X-ray imaging may be used as diagnostic tools.

Treating your loved one

Treatment options may vary depending on the type of arthritis and include physical therapy, lifestyle changes (including exercise and weight control), orthopaedic bracing, medications and dietary supplements (symptomatic or targeted at the disease process causing arthritis). An effective balance should be maintained between dietary supplements and physical exercise. In general, studies have shown that physical exercise of the affected joint can have noticeable improvement in terms of long-term pain relief. Furthermore, exercise of the arthritic joint should be encouraged to maintain the health of the particular joint and the overall body.

Treatment may include:

  • Nonsteroidal anti-inflammatory drugs (NSAIDS) supplementation to reduce pain and inflammation.
  • Dietary provision of nutrients like glucosamine, chondritin sulfate & hyluronic acid salt formulations have been found to be very effective as they provide structural support in form of Gag molecules to build cartilaginous matrix of joints.
  • Combine therapy including NSAIDS, glucosamine, chondritin & hyluronic acid can have a very beneficial effect for overall management of arthritis as it covers all treatment aspects.
  • Along with this, proper nutritious diet and regular exercise will help in effective management of arthritis condition.
  • Proper diet with supplementation of gucosamine, chondritin & hyluronic acid containing formulations can be used as a preventive measure for control of canine arthritis in older dogs.

(Dr Vishal Surve, M.V.Sc, Pharmacology & Toxicology, is Product Executive at Petcare Animal Health, PROVIMI.)

Dog Health

Is Your Dog suffering from Ehrlichiosis

Ticks are carriers of various canine diseases and ehrlichiosis is one of the most fatal diseases caused by them. The greatest challenge in battling ehrlichiosis is in detecting and accurately assessing the clinical signs.

Over the past several decades, ehrlichiosis has emerged as an important threat to dogs worldwide. During recent years, it has gained the reputation as “the AIDS of the canine world.” Dogs not only become clinically affected with ehrlichia or rickettsia but may also serve as a reservoir host.

What is ehrlichiosis?

Canine ehrlichiosis is tick-borne potentially fatal and enigmatic infectious rickettsial disease of dogs, prevalentDog Health in India since 1944. It is colloquially known as canine rickettsiosis, canine typhus, idiopathic haemorrhagic syndrome, canine haemorrhagic fever, tropical canine pancytopenia, Lahore canine fever, Nairobi bleeding disease or tracker dog disease in many parts of the world. Its ability to mimic other diseases and devastating effects makes canine ehrlichiosis a deadly disease. The disease often remains undiagnosed in naturally occurring cases in field owing to nonspecific symptoms, species variation, coand concurrent infections, etc. Hence, timely diagnosis in severely affected chronic cases is escaped leading to futile treatment.

What causes ehrlichiosis?

The disease is caused by obligate intracellular bacteria of genus Ehrlichia of the family Rickettsiacae. Three species of Ehrlichia viz. Ehrlichia canis, E. ewingii and E. platys have been reported in India. Ehrlichia canis, a small and pleomorphic organism that infects circulatory leukocytes, mainly monocytes, causes canine ehrlichiosis. The organism occurs either singly or in compact colonies or inclusions, termed morulae, in the cytoplasm of the infected cells. E. canis, E. ewingii and E. platys are considered strictly canine parasites.

How ehrlichiosis is transmitted?

Canine ehrlichiosis is transmitted between dogs by the brown dog ticks, Rhipicephalus sanguineus and possibly the American dog tick, Dermacentor variabilis. Ehrlichia infections have frequently been reported in dogs with simultaneous infections with Babesia, reflecting concurrent transmission of organisms from commonly infected reservoir ticks. Ehrlichia species can be transmitted by blood transfusion, so blood donors should be screened.

What are the symptoms of ehrlichiosis?

Naturally occurring canine ehrlichiosis is manifested by a wide variety of clinical signs. The greatest challenge in battling ehrlichiosis is in detecting and accurately assessing the clinical signs. The only consistent finding in canine ehrlichiosis is the inconsistency of clinical symptoms. Clinical signs in acute phase of the disease are transient, subtle and mild. Clinical signs mimic those caused by other diseases. Signs may appear 1-3 weeks after infection and often disappear within 2-4 weeks.

Acute phase : Mild depression, anorexia, lethargy, fever, and mild loss in body weight, lymphadenopathy and splenomegaly characterize acute phase. Despite significant thrombocytopenia, haemorrhagic diathesis usually does not occur. Also, ocular signs are not commonly seen at this stage. Whenever ocular signs are present, they involve nearly every structure of the eye (including conjunctivitis, conjunctival or iridal petechiae and echymoses, corneal oedema, hyphema, panuveitis, secondary glaucoma, retinal haemorrhage and detachment). The most frequently observed ocular signs in canine monocytic ehrlichiosis are anterior uveitis, retinal vascular engorgement and tortuosity, perivascular cuffing, diffuse retinitis, retinal haemorrhages and detachment. Clinical signs resolve without treatment in most cases and the dog enters into subclinical phase, which is asymptomatic. During acute phase, transient proteinuria without histologic evidence of glomerular disease has been observed.

Chronic phase : Dogs unable to eliminate infection enter into chronic phase that is characterized by weakness, depression, anorexia, vomiting, emaciation, pale mucosa, erratic fever, peripheral oedema especially of the hind limb and scrotum, and hepato- and splenomegaly. Haemorrhagic episodes (such as skin petechiae and ecchymoses, buccal haemorrhages, epistaxis, haematuria, haematochezia, haemetemesis and hyphema) are also seen in many cases. Interstitial pneumonia, arthritis, renal failure may also occur occasionally. Increased lung sounds on auscultation are attributable to pneumonic changes in the lungs that develop in canine ehrlichiosis or may reflect concurrent cardiopulmonary disease. Neurological signs (such as depression, ataxia, convulsions, cranial nerve deficit, and head tilt) are also seen in canine ehrlichiosis with or without concurrent babesiosis.

Large variations in clinical signs are due to a number of factors including differences in pathogenicity between strains of ehrlichia, breeds of dog, coinfection of ehrlichial species, concurrent infection with other organisms (such as babesia, trypanosoma, dirofiliaria) and/or immune status of the dog.

How ehrlichiosis can be cured?

Treatment of ailing dogs requires professional skill because of many complications and should therefore be undertaken under the advice and care of the competent veterinarian.

Tetracycline, doxycycline, chloramphenicol and imidocarb are the drug of choice and if given timely in appropriate dose schedule are beneficial. Supportive therapy with polyionic isotonic fluids, blood transfusion, and vitamin B complex hastens the recovery. Treatment of severe chronic form of ehrlichiosis is unrewarding in many cases particularly in severely pancytopenic dogs owing to uncontrolled haemorrhages and secondary infections.

For the arrest of haemorrhages during severe chronic phase, blood transfusion is undoubtedly a life saving measure of the first order.

How ehrlichiosis can be prevented?

Prevention of canine ehrlichiosis is possible only with treatment of vertebrate host. Tick population can be controlled by spraying kennels and dipping/ spraying or bathing dogs at an interval of 1-2 weeks, as vector transmission is probably the only means of spread under natural circumstances. Common acaricides such as amitraz, fiproil and pyrethrins are effective in controlling ticks. Long-term use of tetracycline or repository oxytetracycline has been used to prevent or control epizootics of ehrlichiosis. Longer therapy of 1-2 years duration has been recommended in endemic areas so that infected ticks die off. Despite success of the tetracycline in prevention of the ehrlichiosis, it does not seem practical owing to the possibility of future development of resistant strains of E. canis. There is no lasting immunity in case of E. canis infection following treatment. Treated dogs, cleared of infection, become susceptible to re-infection and clinical disease develops despite antibody titre. At present there is no effective anti E. canis vaccine for the prevention or control of canine ehrlichiosis. Because E. canis is not passed transovarially in the tick, it can be eliminated in the environment by tick control or by treatment of all dogs throughout a generation of ticks.

(Dr. J.P. Varshney, B.V.Sc. & A.H.; M.V.Sc (Medicine); and Ph.D. (Vet. Med.), has more than 40 years of clinical experience and has recently superannuated from the post of Principal Scientist (Veterinary Medicine), Division of Medicine, Indian Veterinary Research Institute, Izatnagar, Bareilly. He is in receipt by numerous awards. He can be contacted at 9897224580 or email at dr_jpvarshney@rediffmail.comdrvarshneyjp@yahoo.co.in)